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Figure 4 | BMC Gastroenterology

Figure 4

From: Deficiency of iNOS-derived NO accelerates lipid accumulation-independent liver fibrosis in non-alcoholic steatohepatitis mouse model

Figure 4

Analysis of the mechanisms of liver steatosis. (A) Liver SREBP-1c, ChREBP, DGAT2, PPAR-α1 and MTP mRNA expression levels were all significantly lower in iNOS−/−/HFD mice than in iNOS+/+/HFD mice at 48 weeks. (B) Liver MTP activity was significantly lower in iNOS−/−/HFD mice than in iNOS+/+/HFD mice at 48 weeks. (Data are expressed as the mean ± SEM. * p < 0.05, represents significant difference between iNOS+/+/HFD mice and iNOS−/−/HFD mice).

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BMC Gastroenterology

ISSN: 1471-230X

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