Table 1 Clinical characteristics of the patients
Characteristics | Pethidine group (n = 48) | Placebo group (n = 50) | P value |
|---|---|---|---|
Age (SE) | 46.9 (1.7) | 48.3 (2.0) | NS (p = 0.60) |
Sex ratio (M/F) | 29/19 | 34/16 | NS (p = 0.53) |
BMI | 27.7 (0.8) | 28.2 (0.7) | NS (p = 0.68) |
Indication | |||
Viral Hepatis C | 31 (65%) | 29 (58%) | NS (p = 0.54) |
Other | 17 (35%) | 21 (42%) | NS (p = 0.54) |
Anxiety Score | 37.5 (1.5) | 35.3 (1.7) | NS (p = 0.34) |
Previous anxiety | 8 (17%) | 5 (10%) | NS (p = 0.34) |
Previous biopsy (average) | 0.14 | 0.27 | NS (p = 0.19) |
Current analgesic use | |||
Simple | 7 (15%) | 3 (6%) | NS (p = 0.20) |
Opioids | 6 (13%) | 4 (8%) | NS (p = 0.52) |
Laboratory | |||
INR (SE) | 1.01 (0.01) | 1 (0.02) | NS (p = 0.81) |
Hemoglobin g/L(SE) | 144.0 (2.1) | 145.8 (10.6) | NS (p = 0.54) |
Platelet × 109/L(SE) | 250.6 (11.6) | 231.4 (10.6) | NS (p = 0.23) |
Bilirubin micromol/L (SE) | 10.5 (1.2) | 11.3 (1.7) | NS (p = 0.73) |
ALT u/L (SE) | 85.8 (13.9) | 72.6 (9.9) | NS (p = 0.45) |
Creatinine micromol/L (SE) | 78.8 (2.1) | 82.6 (2.3) | NS (p = 0.23) |
MELD score (SE) | 7 (0.2) | 7.2 (0.2) | NS (p = 0.47) |
Procedure | |||
Number of passes | 1.3 (0.07) | 1.2 (0.06) | NS (p = 0.44) |