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Table 2 Clinical and laboratory features

From: Identifying patients with chronic hepatitis B at high risk of type 2 diabetes mellitus: a cross-sectional study with pair-matched controls

 

DM (n = 207)

Non-DM (n = 207)

P-value

ALT (U/L)

315.54 ± 435.76

245.23 ± 343.80

0.069

AST (U/L)

201.43 ± 272.55

172.34 ± 250.14

0.259

TBIL (μmol/L)

70.86 ± 83.05

57.34 ± 78.99

0.090

ALB (g/L)

34.21 ± 10.45

35.98 ± 9.57

0.073

PT (s)

16.51 ± 6.15

15.48 ± 5.94

0.083

GGT (U/L)

175.11 ± 162.11

121.12 ± 131.38

< 0.001

AFP (ng/mL)

64.96 ± 115.44

56.29 ± 118.27

0.451

HBeAg positivity

95 (45.89%)

66 (31.88%)

0.003

HBV DNA (lg copies/mL)

5.34 ± 1.59

4.78 ± 1.96

0.002

CREA (μmol/L)

82.32 ± 49.62

69.03 ± 38.21

0.002

TG (mmol/L)

1.84 ± 0.93

1.22 ± 0.62

< 0.001

Chol (mmol/L)

4.25 ± 3.06

3.84 ± 2.27

0.122

HDL (mmol/L)

1.08 ± 0.55

1.27 ± 0.69

0.002

LDL (mmol/L)

2.34 ± 1.31

2.10 ± 1.52

0.086

FPG (mmol/L)

8.67 ± 4.20

5.11 ± 1.28

< 0.001

HbA1c (%)

6.81 ± 2.07

6.12 ± 1.48

< 0.001

FPI (μU/mL)

9.42 ± 7.78

6.26 ± 3.33

< 0.001

Steatosis

28 (13.53%)

10 (4.83%)

< 0.001

Cirrhosis

51 (24.64%)

34 (16.43%)

0.040

HCC (%)

12 (5.35%)

7 (3.21%)

0.240

NA treatmenta

79 (38.16%)

73 (35.27%)

0.541

DM treatment

 Diet alone

62 (29.95%)

  

 Metformin

54 (26.09%)

  

 Sulphonylurea

19 (9.18%)

  

 Insulin

72 (34.78%)

  
  1. aNA: nucleos(t)ide analogue.
  2. Reference range of variables: ALT, 0-40 U/L; AST, 0-40 U/L; TBIL, 3.4-17.1 μmol/L; ALB, 35-55 g/L; PT, 12.7-15.4 s; GGT, 0-50U/L; AFP, 0-13.4 ng/mL; HBV DNA, <3 lg copies/mL); CREA, 44-115 μmol/L; TG, 0.48-1.88 mmol/L; Chol, 3.2-6.5 mmol/L; HDL, 0.83-1.96 mmol/L; LDL, 0-3.36 mmol/L; FPG, 3.9-5.6 mmol/L; HbA1c, 4.0-6.0%; FPI, 2-20 μU/mL.