Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical trial

Table 1 Baseline of characteristics of the patients with colorectal liver metastases undergoing surgery at hospital admission in the study (Intention-to-treat)

Index	Control group (n = 68)	PRO group (n = 66)
Sex (Male/Female)	35/33	35/31
Age (Year)	60.16 ± 16.20	65.62 ± 18.18
BMI (kg/m²)	23.06 ± 5.26	22.28 ± 3.66
Location of tumor
ascending colon	15	15
Transverse colon	6	5
Descending colon	12	16
Sigmoid colon	15	11
Rectum	20	19
Time between onset of symptoms and hospital admission (d)	50.28 ± 16.62	55.12 ± 18.26
Preoperative albumin (g/dL)	38.26 ± 8.56	36.98 ± 6.96
Preoperative Hb (g/L)	126.86 ± 32.06	116.22 ± 36.68
Creatinine (mg/dL)	1.26 ± 0.28	1.20 ± 0.62
Operative time (min)	186.28 ± 56.36	199.82 ± 55.98
Intra-operative blood loss (ml)	336.26 ± 182.68	352.56 ± 169.26
Transfusion during operation (ml)	308.12 ± 120.66	329.16 ± 130.58
Usage of supplemental albumin postoperation (g)	22.38 ± 16.36	28.12 ± 20.98
Preoperation prepared time (d)	6.12 ± 3.52	6.68 ± 2.98
Metronidazole (n)	68	66
Penicillin (n)	30	33
Ceftriaxone (n)	38	33
ALT (U/L)	35.68 ± 15.26	32.62 ± 18.86
AST (U/L)	29.68 ± 16.56	28.22 ± 18.86

BMI, body mass index; Hb, hemoglobin; ALT, alanine transarninase (normal value, 0–40 U/L); AST, aspartate aminotransferase (normal value, 0–40 U/L).
There were no significant differences about the characteristics between the two groups.
Quantitative data are expressed as mean ± standard deviation. Numerical data were compared by t test and nominal data by Pearson χ² test or Fisher’s exact test between groups.

ISSN: 1471-230X