Probiotics lowered the postoperative bacterial translocation and endotoxin (Intention-to-treat analysis). PRO effectively decreased the plasma concentration of endotoxin in patients of colorectal liver metastases with normal postoperative intestinal barrier function, compared with the control group (n = 30 for control group and n = 30 for PRO group). Black bar represents the control group, and gray bar represents the PRO group. * (Control) vs. Preoperative, P < 0.05; # (PRO) vs. Preoperative, P < 0.05; * vs. #, P < 0.05. Numerical data are expressed as the means ± standard deviation, and compared by the t-test between groups. Plasma endotoxin was determined preoperatively (hospital admission day), and postoperatively (10 d treatment after surgery).