Tx wk | RBV dose (mg) | RBV level (ng/ml) | SOF dose (mg) | SOF level (ng/ml) | CsA dose (mg) | CsA level (μg/l) | Creat. (μmol/l) | INR | Total bilirubin (μmol/l) | HCV RNA (logIU/ml) |
---|---|---|---|---|---|---|---|---|---|---|
−3 | - | ND | - | - | 50-50 | 79 | 124 | 1.5 | 119 | 5.9 |
−1 | 400 | 873 | - | - | 50-50 | 77 | 121 | 1.7 | 102 | 6.0 |
0 | 400 | 1253 | - | - | 50-50 | 69 | 118 | 1.6 | 101 | 5.8 |
1 | 600 | 1453 | 400 | ND | 50-50 | 67 | 132 | 1.7 | 102 | 2.6 |
2 | 600 | 2161 | 400 | 0.7 | 50-50 | 83 | 113 | 1.7 | 118 | <1.2 (traces) |
3 | 600 | 2234 | 400 | ND | 50-50 | 91 | 138 | 1.7 | 103 | ND |
4 | 400 | 2457 | 400 | 0.8 | 50-50 | 86 | 160 | 1.8 | 168 | ND |
5 | 400 | 1968 | 400 | NA | 50-50 | 103 | 133 | 1.8 | 83 | ND |
6 | 400 | 2789 | 400 | 1.9 | 50-25 | 81 | 173 | 2.0 | 106 | ND |
8 | 400 | 2594 | 400 | ND | 50-25 | 63 | 203 | 1.9 | 129 | ND |
10 | 400 | 2231 | 400 | ND | 50-25 | 79 | 188 | 1.6 | 116 | ND |