The prevalence of gastro-esophageal reflux disease and esophageal dysmotility in Chinese patients with idiopathic pulmonary fibrosis

Table 4 Comparisons of GERD patients with versus without IPF (mean ± SD)

Items		GERD with IPF	GERD without IPF	Independent-Sample t test
Items		N = 43	N = 88	Independent-Sample t test
Age		57.9 ± 10.2	54.2 ± 12.3	P = 0.097
Gender		19/24	39/49	P = 0.989
LESP (mean ± SD)		16.7 ± 9.4	16.3 ± 11.7	P = 0.811
LESRP (mean ± SD)		4.0 ± 5.0	4.8 ± 4.5	P = 0.372
IRP (mean ± SD)		8.2 ± 5.1	7.9 ± 5.6	P = 0.717
UESP (mean ± SD)		66.3 ± 16.5	78.0 ± 29.6	P = 0.018
DEA (mean ± SD)		59.3 ± 37.0	61.6 ± 31.3	P = 0.713
DCI (mean ± SD)		792.2 ± 838.3	592.4 ± 746.4	P = 0.169
Peristalsis n (%)
Normal		24 (55.8)	53 (60.2)	P = 0.630
Weak		19 (44.1)	35 (39.8)
TBTT s		7.4 ± 1.6	7.0 ± 1.3	P = 0.115
CBTR %		56.0 ± 37.0	69.4 ± 34.0	P < 0.001
Acid exposure (pH)		Percent time (%)
Upright		6.4 ± 8.2	5.4 ± 5.7	P = 0.405
Recumbent		4.3 ± 5.9	2.6 ± 4.2	P = 0.099
Total		4.8 ± 4.2	4.2 ± 3.8	P = 0.403
DeMeester score		15.9 ± 12.6	15.0 ± 12.8	P = 0.713
Bolus exposure		All reflux time (%)
Upright		4.6 ± 3.4	3.0 ± 2.5	P = 0.008
Recumbent		1.5 ± 2.1	0.6 ± 1.3	P = 0.022
Total		2.8 ± 2.0	1.9 ± 1.7	P < 0.009
		Reflux Episodes Activity
Distal	Acid	21.1 ± 11.3	21.3 ± 14.8	P = 0.927
Reflux	Nonacid	24.3 ± 14.8	20.1 ± 14.5	P = 0.199
n	Total	45.5 ± 17.9	41.4 ± 23.7	P = 0.326
Proximal	Acid	13.0 ± 9.2	12.1 ± 10.1	P = 0.523
Reflux	Nonacid	11.0 ± 8.5	11.1 ± 10.6	P = 0.615
n	Total	24.3 ± 14.8	23.1 ± 17.3	P = 0.951

GERD: gastro-esophageal reflux disease; IPF: idiopathic pulmonary fibrosis; LESP: lower esophageal sphincter pressure; LESRP: lower esophageal sphincter residual pressure; IRP: integrated relaxation pressure. UESP: upper esophageal sphincter pressure; DCI: distal contractile integral; DEA: distal esophageal amplitude; TBTT: total bolus transmit time; CBTR: complete bolus transit rate.

ISSN: 1471-230X