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Table 2 Results of high-resolution manometry and impedance

From: The prevalence of gastro-esophageal reflux disease and esophageal dysmotility in Chinese patients with idiopathic pulmonary fibrosis

Metrics

IPF patients

Healthy volunteers

Independent-Sample t test or Chi-square test

n = 69

n = 62

Mean ± SD

Mean ± SD

Age

57.9 ± 10.3

32.0 ± 11.3

P < 0.001

Gender (M/F)

31/38

25/37

P = 0.595

LESP mm Hg

17.4 ± 8.8

26.3 ± 10.8

P < 0.001

Hypotensive LES n (%)

13

2

P = 0.005

LESRP mm Hg

4.0 ± 5.0

6.6 ± 4.7

P = 0.008

IRP mm Hg

8.1 ± 4.6

10.4 ± 4.9

P = 0.008

UESP mm Hg

77.7 ± 39.2

101.4 ± 49.5

P < 0.001

DEA mm Hg

59.3 ± 37.0

95.3 ± 35.4

P < 0.001

DCI mm Hg.cm.s

754.1 ± 720.9

1891 ± 1131

P < 0.001

Hiatal hernia n (%)

7 (10.1)

1 (1.6)

P = 0.046

Peristalsis n (%)

Normal

37 (53.6)

57 (91.9)

P < 0.001

Weak

32 (46.4)

5 (8.1)

TBTT s

7.5 ± 1.4

6.9 ± 0.9

P = 0.016

CBTR %

78.0 ± 20.5

90.3 ± 14.0

P < 0.001

  1. Key:
  2. IPF: idiopathic pulmonary fibrosis; LESP: lower esophageal sphincter pressure; LES: lower esophageal sphincter; LESRP: lower esophageal sphincter residual pressure; IRP: integrated relaxation pressure. UESP: upper esophageal sphincter pressure; DCI: distal contractile integral; DEA: distal esophageal amplitude; TBTT: total bolus transmit time; CBTR: complete bolus transit rate.