Figure 5From: The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancerThe SNP rs4648068 influenced cell proliferation, apoptosis percentage and invasive ability. A. Cell proliferation was significantly elevated in 7901-pGL3-GG cells compared with 7901-pGL3-AA cells and 7901-pGL3-mock cells. B. In each box, the lower left corner included viable cells, which were both Annexin V-FITC and PI negative. In the upper left corner, cells are in early apoptosis with Annexin V-FITC positive and PI negative. While the upper right corner included necrotic or late apoptotic cells are both FITC Annexin V and PI positive. In 7901-pGL3-GG cells, the percentage of apoptosis cells decreased significantly, compared with 7901-pGL3-AA. C. The invasion ability was increased in 7901-pGL3-GG cells (c) than control cells (a, b). 200×. a, 7901-pGL3-AA cells; b, 7901-pGL3-mock cells; c, 7901-pGL3-GG cells. Data were assessed by One-way ANOVA analysis. ***P < 0.01; **P < 0.05.Back to article page