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Figure 5 | BMC Gastroenterology

Figure 5

From: The NFKB1 polymorphism (rs4648068) is associated with the cell proliferation and motility in gastric cancer

Figure 5

The SNP rs4648068 influenced cell proliferation, apoptosis percentage and invasive ability. A. Cell proliferation was significantly elevated in 7901-pGL3-GG cells compared with 7901-pGL3-AA cells and 7901-pGL3-mock cells. B. In each box, the lower left corner included viable cells, which were both Annexin V-FITC and PI negative. In the upper left corner, cells are in early apoptosis with Annexin V-FITC positive and PI negative. While the upper right corner included necrotic or late apoptotic cells are both FITC Annexin V and PI positive. In 7901-pGL3-GG cells, the percentage of apoptosis cells decreased significantly, compared with 7901-pGL3-AA. C. The invasion ability was increased in 7901-pGL3-GG cells (c) than control cells (a, b). 200×. a, 7901-pGL3-AA cells; b, 7901-pGL3-mock cells; c, 7901-pGL3-GG cells. Data were assessed by One-way ANOVA analysis. ***P < 0.01; **P < 0.05.

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