Skip to main content
Figure 2 | BMC Gastroenterology

Figure 2

From: Heterogeneity of amplification of HER2, EGFR, CCND1 and MYC in gastric cancer

Figure 2

HER2 FISH and IHC findings in primary gastric cancers and their metastases in 19 cancers with HER2 amplification.a“Tumor” indicates the cases number referred to in the text. bThe FISH and IHC results of individual tissue spots are indicated by integers reflecting the copy numbers of centromere 17/HER2 (i.e. 2/20, black face) and the HercepTest IHC score (i.e. 3, white face) in the primary and metastases spots. Green color in the primary/metastases spots area indicates high-level HER2 amplification or positive IHC findings, orange color indicates low-level amplification, and blue color indicates negative IHC findings. cBold black outline in the “metastases spots” highlights spots that were derived from the same metastasis. d“Heterogeneity” indicates whether FISH or IHC findings were homogeneous (Homo.) or heterogeneous (Hetero). e“Validation” shown the large section FISH results in 3 cases obtained from the primary cancer (case #11 and #19) and from the amplified metastasis (#12).

Back to article page