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Table 2 Pooled analysis of studies exploring the role of TLR4 Asp299Gly in UC

From: Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis

Study Cases (Events/Total) Controls (Events/Total) Odds ratio 95% CI P value
Arnott et al. 2004 [ [31]] 35/492 33/378 0,801 0,49 to 1,31  
Franchimont et al. (1) 2004 [ [32]] 32/326 14/278 2,052 1,07 to 3,93  
Torok et al. 2004 [ [33]] 18/196 12/290 2,343 1,10 to 4,98  
Braat et al. 2005 [ [34]] 24/452 13/274 1,126 0,56 to 2,25  
Gazouli et al. 2005 [ [36]] 6/170 6/200 1,183 0,37 to 3,73  
Oostenbrug et al. 2005 [ [37]] 21/358 27/592 1,304 0,72 to 2,34  
Baumgart et al. 2007 [ [21]] (1) 8/236 16/404 0,851 0,36 to 2,02  
Baumgart et al. 2007 [ [21]] (2) 24/290 49/806 1,394 0,84 to 2,31  
Browning et al. 2007 [ [42]] 51/810 44/832 1,203 0,79 to 1,82  
Riis et al. 2007 [ [43]] 53/808 152/1236 0,501 0,36 to 0,69  
De Ridder et al. 2007 [ [23]] (1) 33/452 20/488 1,843 1,04 to 3,26  
De Ridder et al. 2007 [ [23]] (2) 4/62 20/488 1,614 0,53 to 4,88  
Rigoli et al. 2008 [ [45]] 3/90 8/206 0,853 0,22 to 3,29  
Manolakis et al. 2013 [ [46]] 41/374 33/548 1,921 1,19 to 3,10  
Current study 2014 6/68 10/224 2,071 0,72 to 5,92  
Total (fixed effects) 359/5184 457/7244 1,092 0,94 to 1,26 0.20
Total (random effects) 359/5184 457/7244 1,268 0,95 to 1,69