Table 2 Pooled analysis of studies exploring the role of TLR4 Asp299Gly in UC

Arnott et al. 2004 [ [31]]

35/492

33/378

0,801

0,49 to 1,31

Franchimont et al. (1) 2004 [ [32]]

32/326

14/278

2,052

1,07 to 3,93

Torok et al. 2004 [ [33]]

18/196

12/290

2,343

1,10 to 4,98

Braat et al. 2005 [ [34]]

24/452

13/274

1,126

0,56 to 2,25

Gazouli et al. 2005 [ [36]]

6/170

6/200

1,183

0,37 to 3,73

Oostenbrug et al. 2005 [ [37]]

21/358

27/592

1,304

0,72 to 2,34

Baumgart et al. 2007 [ [21]] (1)

8/236

16/404

0,851

0,36 to 2,02

Baumgart et al. 2007 [ [21]] (2)

24/290

49/806

1,394

0,84 to 2,31

Browning et al. 2007 [ [42]]

51/810

44/832

1,203

0,79 to 1,82

Riis et al. 2007 [ [43]]

53/808

152/1236

0,501

0,36 to 0,69

De Ridder et al. 2007 [ [23]] (1)

33/452

20/488

1,843

1,04 to 3,26

De Ridder et al. 2007 [ [23]] (2)

4/62

20/488

1,614

0,53 to 4,88

Rigoli et al. 2008 [ [45]]

3/90

8/206

0,853

0,22 to 3,29

Manolakis et al. 2013 [ [46]]

41/374

33/548

1,921

1,19 to 3,10

Current study 2014

6/68

10/224

2,071

0,72 to 5,92

Total (fixed effects)

359/5184

457/7244

1,092

0,94 to 1,26

0.20

Total (random effects)

359/5184

457/7244

1,268

0,95 to 1,69