From: Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms: New data and a meta-analysis
Parameter | N | Asp299gly (%) | P value | Chi-square test | Thr399Ile (%) | P value | Chi-square test | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
AA | AG | GG | CC | CT | TT | Â | Â | ||||
Age of onset | 34 | Â | Â | Â | 0.35 | 0.89 | Â | Â | Â | 0.34 | 2.13 |
<17Â years | - | - | - | Â | Â | Â | - | - | Â | Â | Â |
17-40 | 20 | 18 (90.0) | 2 (10.0) | - | Â | Â | 19 (95.0) | 1 (5.0) | - | Â | Â |
>40Â years | 14 | 10 (71.4) | 4 (28.6) | - | Â | Â | 13 (92.9) | - | 1 (7.1) | Â | Â |
Sex | 34 | Â | Â | Â | 0.89 | 0.018 | Â | Â | Â | 0.36 | 2.06 |
Woman | 15 | 13 (86.7) | 2 (13.3) | - | Â | Â | 14 (93.3) | 1 (6.7) | - | Â | Â |
Man | 19 | 15 (78.9) | 4 (21.1) | - | Â | Â | 18 (94.7) | - | 1 (5.3) | Â | Â |
Extent of the disease | 34 | Â | Â | Â | 0.31 | 3.55 | Â | Â | Â | 0.16 | 9.34 |
E1 | 4 | 2 (50.0) | 2 (50.0) | - | Â | Â | 3 (75.0) | - | 1 (25.0) | Â | Â |
E2 | 15 | 13 (86.7) | 2 (13.3) | - | Â | Â | 15 (100.0) | - | - | Â | Â |
E3 | 2 | 2 (100.0) | - | - | Â | Â | 2 (100.0) | - | - | Â | Â |
E4 | 13 | 11 (84.6) | 2 (15.4) | - | Â | Â | 12 (92.3) | 1 (7.7) | - | Â | Â |
SFC | 34 | Â | Â | Â | 0.39 | 0.74 | Â | Â | Â | 0.97 | 0.06 |
Presence | 1 | 1 (100.0) | - | - | Â | Â | 1 (100.0) | - | Â | Â | Â |
Absence | 33 | 27 (81.8) | 6 (18.2) | - | Â | Â | 31 (93.9) | 1 (3.0) | 1 (3.0) | Â | Â |
Smoking | 34 | Â | Â | Â | 0.93 | 0.008 | Â | Â | Â | 0.20 | 3.17 |
Presence | 9 | 7 (77.8) | 2 (22.2) | - | Â | Â | 8 (88.9) | - | 1 (11.1) | Â | Â |
Absence | 25 | 21 (84.) | 4 (16.0) | - | Â | Â | 24 (96.0) | 1 (4.0) | - | Â | Â |
EIM | 34 | Â | Â | Â | 0.89 | 0.018 | Â | Â | Â | 0.35 | 2.05 |
Presence | 19 | 15 (78.9) | 4 (21.1) | - | Â | Â | 18 (94.7) | - | 1 (5.3) | Â | Â |
Absence | 15 | 13 (86.7) | 2 (13.3) | - | Â | Â | 14 (93.3) | 1 (6.7) | - | Â | Â |
Surgery | 34 | Â | Â | Â | 0.004 | 8.3 | Â | Â | Â | 0.08 | 4.97 |
Presence | 6 | 2 (33.3) | 4 (66.7) | - | Â | Â | 5 (83.3) | 1 (16.7) | - | Â | Â |
Absence | 28 | 26 (92.9) | 2 (7.1) | - | Â | Â | 27 (96.4) | - | 1 (3.6) | Â | Â |