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Table 1 Hazard ratios for uncomplicated peptic ulcer disease associated with factors assessed at the start date (cohort analysis)

From: Risk of uncomplicated peptic ulcer disease in a cohort of new users of low-dose acetylsalicylic acid for secondary prevention of cardiovascular events

  Adjusted HR (95% CI) a
Sex
  Male 1 (-)
  Female 1.19 (0.95-1.50)
Age at start date, years
  50-59 1 (-)
  60-69 1.08 (0.79-1.47)
  70-79 1.26 (0.92-1.73)
  80-84 1.69 (1.05-2.74)
Year of start date
  2000-2001 1 (-)
  2002-2003 1.02 (0.77-1.35)
  2004-2005 0.84 (0.61-1.17)
  2006-2007 0.84 (0.57-1.22)
ASA indication
  Cerebrovascular disease 1 (-)
  Myocardial infarction 1.12 (0.82-1.53)
  Ischaemic heart disease 1.06 (0.81-1.39)
  Unstable angina 1.25 (0.60-2.59)
PPI use at start date
  No 1 (-)
  Yes 1.23 (0.93-1.62)
History of PUD at start date
  No 1 (-)
  Yes 2.22 (1.60-3.09)
  1. aHRs estimated by Cox regression analyses and adjusted for all variables in the table.
  2. Abbreviations: ASA-Acetylsalicylic acid; CI-Confidence interval; HRs-Hazard ratios; PPI-Proton pump inhibitor; PUD-Peptic ulcer disease.