Figure 1

Dose–response Curves of SB-269970 and SB-258719 administration. Rate of liver regeneration at 24 h after 60-70% partial hepatectomy as evaluated by [³H]-thymidine incorporation into hepatic DNA in rats having administered different doses of SB-269970 (0.5, 1, 1.5, 2, and 2.5 mg/kg body weight) and SB-258719 (0.5, 1, 2, 4 and 5 mg/kg body weight) intraperitoneally at 16 h after partial hepatectomy. Results represent the findings from at least five rats. Values are expressed as means ± SE.