Skip to main content

Table 1 Demographic and clinical characteristics of the study patients

From: Frequency and risk factors for rebleeding events in patients with small bowel angioectasia

Characteristics

Total

Endoscopic treatment (+)

Endoscopic treatment (-)

P value*

Number

68

22

46

 

Bleeding pattern (overt/occult)

40/28

19/3

21/25

0.002

Number of angioectasia, mean (median)

3.4 (2.5)

4.0 (2.0)

3.1 (3.0)

0.68

Age, year, mean ± SD

67.6 ± 12.8

66.9 ± 10.9

66.5 ± 13.6

0.30

Sex, Male/Female

38/30

11/11

27/19

0.60

Drinking history (%)

23 (33.8)

11 (50.0)

12 (26.0)

0.06

Smoking history (%)

24 (35.3)

7 (31.8)

17 (37.0)

0.79

Blood transfusion (%)

31 (45.6)

17 (77.3)

14 (30.4)

0.001

Minimum hemoglobin value, g/dl

9.3 ± 2.7

8.0 ± 2.0

9.9 ± 2.9

0.006

Follow-up duration, month, median (IQR)

30.5 (16.5-47.0)

34.0 (21.0-46.5)

30.0 (18.0-46.0)

0.76

Rebleeding rate, number (%)

23 (33.8)

5 (22.7)

18 (39.1)

0.27

Iron replacement therapy after OGIB, number (%)

59 (86.8)

20 (91.0)

39 (84.8)

0.71

Comorbidity, number (%)

    

Hypertension

46 (67.6)

19 (86.4)

27 (58.7)

0.03

Diabetes

15 (22.1)

7 (31.8)

8 (17.4)

0.22

Cardiovascular disease

18 (26.5)

8 (36.4)

10 (21.7)

0.25

Cerebral infarction

9 (13.2)

3 (13.6)

6 (13.0)

>0.99

CKD, ≥ stage 4

17 (86.4)

8 (36.4)

9 (19.6)

0.15

Liver cirrhosis

3 (4.4)

1 (4.5)

2 (4.3)

>0.99

Medication used, number (%)

    

Warfarin

9 (13.2)

4 (18.2)

5 (10.9)

0.46

LDA

27 (39.7)

10 (45.5)

17 (37.0)

0.60

Thienopyridine

9 (13.2)

3 (13.6)

6 (13.0)

>0.99

NSAIDs

7 (10.3)

2 (9.1)

5 (10.9)

>0.99

H2-blockers

17 (25.0)

5 (22.7)

12 (26.1)

>0.99

PPIs

25 (36.8)

8 (36.4)

17 (37.0)

>0.99

Rebamipide

10 (14.7)

4 (18.2)

6 (13.0)

>0.99

  1. Abbreviations: IQR, interquartile range; CKD, chronic kidney disease; LDA, low-dose aspirin; NSAIDs, nonsteroidal anti-inflammatory drugs; H2-blockers, histamine H2 receptor antagonists; PPIs, proton pump inhibitors.
  2. Variable definitions: Alcohol history was defined as positive if the subject’s alcohol consumption exceeded 20 g/day. Smoking history was defined as positive if the subject had smoked more than 10-pack years and was still smoking or had quit within the previous 10 years. History of antiplatelet drug and/or NSAID use was defined as positive if the patient had been taking at least 1 pill per day of either of these drugs for more than 1 week within 1 month prior to the CE. History of anticoagulant drug use was defined as positive if the patient had been taking at least 1 pill of anticoagulant drug per day within one week prior to the CE.
  3. *Differences between endoscopic treatment (+) and (-) were calculated by Fisher's exact test or unpaired student t-test.