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Table 2 Clinical and genetic features of the 6 celiac disease patients developing complications

From: The changing clinical profile of celiac disease: a 15-year experience (1998-2012) in an Italian referral center

Pts Gender Age at diagnosis (yrs) Clinical phenotype HLA Delay in CD diagnosis (yrs) Age at complication (yrs) Complication Outcome
#1 M 42 Classical DQ2 + ° 8 45 EATCL Alive, 54 yrs
#2 F 66 Classical DQ2+ 10 70 RCD type 1 Alive, 73 yrs
#3 F 52 Classical DQ2 + ° 5 56 RCD type 1 Alive, 64 yrs
#4 F 48 Classical DQ2+ 6 51 Small bowel carcinoma Dead, 53 yrs
#5 F 65 Classical DQ2 + ° 11 65 Small bowel carcinoma Alive, 76 yrs
#6 F 55 Classical DQ2+ 7 59 RCD type 1 Alive, 66 yrs
  1. EATCL, enteropathy associated T-cell lymphoma; RCD, refractory celiac disease.
  2. °DQ2 homozygosis (DQB1 *0201 on both chromosomes) was established in case #1, #3 and #5.