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Table 2 Clinical and genetic features of the 6 celiac disease patients developing complications

From: The changing clinical profile of celiac disease: a 15-year experience (1998-2012) in an Italian referral center

Pts

Gender

Age at diagnosis (yrs)

Clinical phenotype

HLA

Delay in CD diagnosis (yrs)

Age at complication (yrs)

Complication

Outcome

#1

M

42

Classical

DQ2 + °

8

45

EATCL

Alive, 54 yrs

#2

F

66

Classical

DQ2+

10

70

RCD type 1

Alive, 73 yrs

#3

F

52

Classical

DQ2 + °

5

56

RCD type 1

Alive, 64 yrs

#4

F

48

Classical

DQ2+

6

51

Small bowel carcinoma

Dead, 53 yrs

#5

F

65

Classical

DQ2 + °

11

65

Small bowel carcinoma

Alive, 76 yrs

#6

F

55

Classical

DQ2+

7

59

RCD type 1

Alive, 66 yrs

  1. EATCL, enteropathy associated T-cell lymphoma; RCD, refractory celiac disease.
  2. °DQ2 homozygosis (DQB1 *0201 on both chromosomes) was established in case #1, #3 and #5.