Skip to main content

Table 1 Abnormal values and values within normal ranges of serum anti-OmpC IgA (>25U/mL vs. <20U/mL), anti-GP2 IgG (>20U/mL vs. <15U/mL) and anti-GP2 IgA (>20U/mL vs. <15U/mL) in controls, CD patients and UC patients

From: Anti-Outer membrane protein C and anti-glycoprotein 2 antibodies in inflammatory bowel disease and their association with complicated forms of Crohn’s disease

  controls CD UC
Anti-OmpC IgA >25U/mL 8/45 (18%) 53/86 (62%) 13/25 (52%)
Anti-OmpC IgA <20U/mL 26/45 (58%) 22/86 (26%) 6/25 (24%)
Anti-GP2 IgG >20U/mL 1/45 (2%) 27/86 (31%) 4/25 (16%)
Anti-GP2 IgG <15U/mL 42/45 (93%) 49/86 (57%) 21/25 (84%)
Anti-GP2 IgA >20U/mL 8/45 (18%) 43/86 (50%) 2/25 (8%)
Anti-GP2 IgA <15U/mL 33/45 (73%) 35/86 (41%) 21/25 (84%)
Sens/Spec/NPV/PPV of anti-OmpC IgA [%]   71/76/54/87 68/76/81/62
Sens/Spec/NPV/PPV of anti-GP2 IgG [%]   36/98/47/96 16/98/67/80
Sens/Spec/NPV/PPV of anti-GP2 IgA [%]   55/80/49/84 9/80/61/20
  1. Sens: sensitivity, spec: specificity, NPV: negative predictive value, PPV: positive predictive value.