Table 2 Genotype frequency of the oxytocin receptor (OXTR) 5'promoter region rs3806675 G>A in patients with lactase non-persistence or lactase persistence
Genotype | G/G n (%) | A/G n (%) | A/A n (%) | P value |
|---|---|---|---|---|
Constipated-dominated IBS (n:34) | 11 (32.4) | 18 (52.9) | 5 (14.7) | |
Mixed IBS (n:59) | 15 (25.4) | 33 (55.9) | 11 (18.6) | P = 0.44* |
Diarrhoea-dominated IBS (n:35) | 13 (37.1) | 20 (57.1) | 2 (5.7) | |
Lactase persistence (n:254) | 69 (27.2) | 128 (50.4) | 56 (22.0) | |
Lactase non-persistence (n:154) | 55 (35.7) | 76 (49.4) | 22 (14.3) | P = 0.07** |
Controls (n:299) | 101 (33.8) | 146 (48.8) | 52 (17.4) |