Skip to main content

Table 2 Genotype frequency of the oxytocin receptor (OXTR) 5'promoter region rs3806675 G>A in patients with lactase non-persistence or lactase persistence

From: Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms

Genotype G/G
n (%)
A/G
n (%)
A/A
n (%)
P value
Constipated-dominated IBS (n:34) 11 (32.4) 18 (52.9) 5 (14.7)  
Mixed IBS (n:59) 15 (25.4) 33 (55.9) 11 (18.6) P = 0.44*
Diarrhoea-dominated IBS (n:35) 13 (37.1) 20 (57.1) 2 (5.7)  
Lactase persistence (n:254) 69 (27.2) 128 (50.4) 56 (22.0)  
Lactase non-persistence (n:154) 55 (35.7) 76 (49.4) 22 (14.3) P = 0.07**
Controls (n:299) 101 (33.8) 146 (48.8) 52 (17.4)  
  1. * = Comparisons made between subgroups of patients with Irritable Bowel Syndrome (IBS).
  2. ** = Comparisons made between controls and lactase persistent- and lactase non-persistent subjects.
  3. Fisher's exact test.