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Table 1 Genotype frequency of the oxytocin (OXT) promoter region rs6133010 A>G in patients, subjects and controls

From: Polymorphism in the oxytocin promoter region in patients with lactase non-persistence is not related to symptoms

Genotype

A

N (%)

A/G

n (%)

G/G

N (%)

P value

Constipation-predominated IBS (n:35)

30 (85.7)

5 (14.3)

0 (0.0)

 

Mixed IBS (n:59)

49 (83.1)

10 (16.9)

0 (0.0)

P = 0.60*

Diarrhoea-predominated IBS (n:35)

26 (74.3)

9 (25.7)

0 (0.0)

 

Lactase persistence (n:254)

208 (81.9)

46 (18.1)

0 (0.0)

 

Lactase non-persistence (n:154)

111 (72.1)

42 (27.3)

1 (0.6)

P = 0.08**

Controls (n:299)

240 (80.3)

58 (19.4)

1 (0.3)

 
  1. * = Comparisons made between subgroups of patients with Irritable Bowel Syndrome (IBS).
  2. ** = Comparisons made between controls and lactase persistent- and lactase non-persistent subjects.
  3. Fisher's exact test.