Table 2 Distribution of cagA and vacA alleles in patients
Diagnosis in patients n = 224 | |||||
|---|---|---|---|---|---|
Virulence marker | Non ulcer dyspepsia n = 120 | Gastric ulcer n = 32 | Gastric carcinoma n = 40 | Duodenal ulcer n = 32 | P value* |
CagA | |||||
Positive | 51 (42) | 20(62) | 31(77) | 23(72) | <0.001 |
Negative | 69 (58) | 12(38) | 9(23) | 9(28) | |
VacAs1a | |||||
Positive | 79 (66) | 25(78) | 31(77) | 19(59) | 0.211 |
Negative | 41 (34) | 7(22) | 9(23) | 13(41) | |
VacAs1b | |||||
Positive | 30 (25) | 12 (37) | 17 (42) | 13 (41) | 0.100 |
Negative | 90 (75) | 20(63) | 23(58) | 19 (59) | |
VacAm1 | |||||
Positive | 50 (42) | 27(84) | 29(72) | 29(91) | <0.001 |
Negative | 70 (58) | 5(16) | 11(28) | 3(9) | |
VacAm2 | |||||
Positive | 74 (62) | 15(47) | 15(37) | 12(37) | <0.01 |
Negative | 46 (38) | 17(53) | 25(63) | 20(63) | |
VacAs1am1 | |||||
Positive | 38 (32%) | 23(72) | 23(56) | 17(53) | <0.001 |
Negative | 82 (68%) | 9(28) | 17(44) | 15(47) | |
VacAs1bm1 | |||||
Positive | 13 (11) | 9(28) | 11(28) | 12(38) | <0.001 |
Negative | 107 (89) | 23(72) | 29(82) | 20(62) | |
CagA s1am1 | |||||
Positive | 22 (18) | 11(34) | 22(55) | 11(34) | <0.001 |
Negative | 98(82) | 21(66) | 18(45) | 21(66) | |
CagA s1bm1 | |||||
Positive | 19 (16) | 11(34) | 7(18) | 5(16) | 0.01 |
Negative | 101 (84) | 21(66) | 33 (82) | 27(84) | |
vacAi | |||||
i1 and i2 positive | 4(3) | 0 | 2(5) | 0 | < 0.001 |
i1 and i2 negative | 2(2) | 2(6) | 1(3) | 0 | |
i1 positive | 5(4) | 27(85) | 33(82) | 27(84) | |
i2 positive | 109(91) | 3(9) | 4(10) | 5(16) | |