Effects of esomeprazole treatment for gastroesophageal reflux disease on quality of life in 12- to 17-year-old adolescents: an international health outcomes study

Table 1 Mean changes in QOLRAD total and domain scores from baseline to final visit (n = 134).

QOLRAD Domain	Change in Mean Scores^a	Number of patients who significantly improved, n (%)^b	Number of patients who significantly worsened, n (%)^b
Emotional distress	0.83	67 (50.0)	10 (7.5)
Sleep disturbance	0.65	61 (45.5)	13 (9.7)
Food/drink problems	1.07	85 (63.4)	9 (6.7)
Vitality	0.79	73 (54.5)	17 (12.7)
Physical/social functioning	0.50	56 (41.8)	13 (9.7)
Total score	0.77	-	-

Abbreviation: QOLRAD, Quality of Life in Reflux and Dyspepsia questionnaire.
^a P < .0001; ^bSignificant improvement and significant worsening defined as a change in score of 0.5 from baseline.

ISSN: 1471-230X