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Table 5 The diagnostic properties (sensitivity, specificity, positive and negative predictive values, accuracy and likelihood ratios (LR)) for the variables in the study with different cut-off levels (normal values).

From: A comparison of diagnostic tests for lactose malabsorption - which one is the best?

Variable

Normal value

Sensitivity

Specificity

PPV

NPV

Accuracy

LR +

LR-

H2 + CH4x2

<53 ppm

44.4%

100%

100%

92.4%

92.9%

Inde-finite

0.56

H2 + CH4x2

<18 ppm

100%

90.2%

60%

100%

91.4%

10.2

0

H2 + CH4

<17 ppm

88.9%

91.8%

61.5%

98.2%

91.4%

10.8

0.12

H2

<16 ppm

77.8%

93.4%

63.6%

96.6%

91.4%

11.9

0.24

s-glucose-increase

>0.9 mmol/L

77.8%

93.4%

63.6%

96.6%

91.4%

11.9

0.24

Any symptom-ELL

Absent

85.7%

78.4%

35.3%

97.6%

79.3%

4.0

0.18

  1. The results are based on all performed tests.