dbSNP id | CARD8 Position | MAF case | MAF cont | ORallelic[CI95%] | Pallelic | PHAP2 | PHAP3 | PHAP4 | PHAP5 |
---|---|---|---|---|---|---|---|---|---|
1044 CRC patients vs 724 sex-matched control individuals | |||||||||
   rs4802445 | 3'UTR | 0.44 | 0.45 | 0.95 [0.83-1.08] | 0.431 | 0.549 | 0.540 | 0.615 | 0.305 |
   rs1966625 | intron | 0.09 | 0.10 | 0.90 [0.72-1.13] | 0.360 | 0.552 | 0.463 | 0.368 | 0.726 |
   rs16981829 | intron | 0.33 | 0.33 | 1.00 [0.86-1.15] | 0.976 | 0.998 | 0.419 | 0.712 | 0.697 |
   rs11881179 | V68I | 0.001 | 0.001 | 1.04 [0.17-6.25] | 0.964 | 0.975 | 0.999 | 0.971 | 0.518 |
   rs4802449 | intron | 0.34 | 0.34 | 0.99 [0.86-1.14] | 0.856 | 0.966 | 0.828 | 0.406 | 0.488 |
   rs2043211 | C10Ter | 0.32 | 0.32 | 1.01 [0.88-1.17] | 0.857 | 0.907 | 0.474 | 0.477 | 0.549 |
   rs6509364 | intron | 0.34 | 0.34 | 1.02 [0.88-1.17] | 0.820 | 0.593 | 0.642 | 0.661 | 0.602 |
   rs11670259 | intron | 0.35 | 0.34 | 1.05 [0.91-1.21] | 0.486 | 0.483 | 0.592 | 0.675 | 0.517 |
   rs12984929 | intron | 0.41 | 0.39 | 1.09 [0.95-1.25] | 0.235 | 0.545 | 0.760 | 0.343 | 0.417 |
   rs11672725 | intron | 0.20 | 0.19 | 1.02 [0.86-1.21] | 0.819 | 0.819 | 0.865 | 0.350 | -# |
   rs10500300 | intron | 0.08 | 0.08 | 1.06 [0.83-1.36] | 0.619 | 0.820 | 0.226 | -# | -# |
   rs6509368 | intron | 0.44 | 0.44 | 1.02 [0.89-1.16] | 0.816 | 0.544 | -# | -# | -# |
   rs10405717 | intron | 0.15 | 0.17 | 0.90 [0.75-1.07] | 0.238 | -# | -# | -# | -# |
143 CRC patients (age at diagnosis ≤50) vs 639 sex-matched control individuals | |||||||||
   rs4802445 | 3'UTR | 0.4 | 0.45 | 0.81 [0.62-1.05] | 0.106 | 0.197 | 0.310 | 0.352 | 0.321 |
   rs1966625 | intron | 0.07 | 0.1 | 0.73 [0.45-1.18] | 0.200 | 0.322 | 0.373 | 0.388 | 0.692 |
   rs16981829 | intron | 0.31 | 0.33 | 0.94 [0.71-1.24] | 0.663 | 0.603 | 0.388 | 0.647 | 0.729 |
   rs11881179 | V68I | 0 | 0.002 | N/A* | 0.503 | 0.166 | 0.280 | 0.372 | 0.039 |
   rs4802449 | intron | 0.39 | 0.34 | 1.25 [0.96-1.63] | 0.100 | 0.232 | 0.341 | 0.028 | 0.131 |
   rs2043211 | C10Ter | 0.29 | 0.32 | 0.84 [0.63-1.11] | 0.225 | 0.251 | 0.024 | 0.144 | 0.067 |
   rs6509364 | intron | 0.32 | 0.33 | 0.94 [0.72-1.24] | 0.668 | 0.004 | 0.031 | 0.020 | 0.092 |
   rs11670259 | intron | 0.43 | 0.34 | 1.46 [1.13-1.90] | 0.004 a | 0.023 | 0.018 | 0.118 | 0.159 |
   rs12984929 | intron | 0.37 | 0.39 | 0.93 [0.71-1.21] | 0.595 | 0.865 | 0.441 | 0.332 | 0.407 |
   rs11672725 | intron | 0.2 | 0.2 | 1.04 [0.75-1.43] | 0.830 | 0.755 | 0.575 | 0.615 | -# |
   rs10500300 | intron | 0.09 | 0.08 | 1.14 [0.72-1.80] | 0.583 | 0.590 | 0.750 | -# | -# |
   rs6509368 | intron | 0.47 | 0.44 | 1.1 [0.85-1.42] | 0.479 | 0.585 | -# | -# | -# |
   rs10405717 | intron | 0.17 | 0.16 | 1.08 [0.77-1.52] | 0.648 | -# | -# | -# | -# |