dbSNP id | CARD4 Position | MAF case | MAF cont | ORallelic[CI95%] | Pallelic | PHAP2 | PHAP3 | PHAP4 | PHAP5 |
---|---|---|---|---|---|---|---|---|---|
1044 CRC patients vs 724 sex-matched control individuals | |||||||||
   Rs5743369 | intron | 0.15 | 0.16 | 0.93 [0.78-1.12] | 0.445 | 0.371 | 0.252 | 0.333 | 0.421 |
   Rs10267377 | intron | 0.30 | 0.28 | 1.09 [0.94-1.27] | 0.253 | 0.222 | 0.322 | 0.556 | 0.274 |
   Rs2907748 | intron | 0.26 | 0.23 | 1.14 [0.98-1.34] | 0.103 | 0.415 | 0.748 | 0.637 | 0.546 |
   ND1+32656 | intron | 0.26 | 0.24 | 1.13 [0.96-1.32] | 0.131 | 0.512 | 0.405 | 0.238 | 0.148 |
   Rs2907749 | intron | 0.29 | 0.27 | 1.1 [0.95-1.28] | 0.234 | 0.365 | 0.095 | 0.112 | 0.199 |
   Rs2284358 | intron | 0.29 | 0.27 | 1.09 [0.94-1.26] | 0.304 | 0.618 | 0.152 | 0.204 | 0.184 |
   Rs2075820 | E266K | 0.25 | 0.27 | 0.93 [0.80-1.09] | 0.363 | 0.666 | 0.367 | 0.374 | 0.294 |
   Rs7789045 | intron | 0.46 | 0.47 | 0.96 [0.84-1.10] | 0.558 | 0.755 | 0.366 | 0.35 | 0.384 |
   rs2075819 | intron | 0.27 | 0.29 | 0.92 [0.79-1.07] | 0.307 | 0.092 | 0.086 | 0.22 | 0.343 |
   rs3823773 | intron | 0.12 | 0.12 | 0.98 [0.79-1.21] | 0.891 | 0.984 | 0.986 | 0.864 | 0.382 |
   rs736781 | intron | 0.19 | 0.19 | 0.99 [0.83-1.17] | 0.919 | 0.941 | 0.765 | 0.283 | 0.352 |
   rs2893375 | intron | 0.17 | 0.17 | 1.03 [0.86-1.23] | 0.783 | 0.911 | 0.162 | 0.255 | 0.172 |
   rs2529440 | intron | 0.42 | 0.42 | 1.02 [0.89-1.17] | 0.777 | 0.364 | 0.243 | 0.175 | -# |
   rs4720004 | intron | 0.15 | 0.14 | 1.13 [0.93-1.37] | 0.236 | 0.525 | 0.327 | -# | -# |
   rs932272 | intron | 0.40 | 0.39 | 1.04 [0.91-1.20] | 0.536 | 0.286 | -# | -# | -# |
   rs17770244 | intron | 0.06 | 0.06 | 1.01 [0.76-1.35] | 0.927 | -# | -# | -# | -# |
143 CRC patients (age at diagnosis ≤ 50) vs 639 sex-matched control individuals | |||||||||
   rs5743369 | intron | 0.12 | 0.16 | 0.7 [0.47-1.03] | 0.065 | 0.069 | 0.09 | 0.19 | 0.22 |
   rs10267377 | intron | 0.34 | 0.29 | 1.26 [0.96-1.66] | 0.093 | 0.212 | 0.41 | 0.55 | 0.36 |
   rs2907748 | intron | 0.28 | 0.23 | 1.3 [0.97-1.74] | 0.075 | 0.273 | 0.52 | 0.32 | 0.15 |
   ND1+32656 | intron | 0.29 | 0.24 | 1.31 [0.98-1.76] | 0.065 | 0.263 | 0.13 | 0.04 | 0.10 |
   rs2907749 | intron | 0.32 | 0.27 | 1.25 [0.95-1.66] | 0.111 | 0.06 | 0.007 | 0.04 | 0.10 |
   rs2284358 | intron | 0.32 | 0.28 | 1.25 [0.95-1.65] | 0.117 | 0.01 | 0.02 | 0.06 | 0.07 |
   rs2075820 | E266K | 0.19 | 0.27 | 0.62 [0.45-0.86] | 0.004a | 0.009 | 0.03 | 0.04 | 0.06 |
   rs7789045 | intron | 0.43 | 0.47 | 0.84 [0.65-1.09] | 0.188 | 0.01 | 0.01 | 0.04 | 0.06 |
   rs2075819 | intron | 0.21 | 0.29 | 0.62 [0.46-0.85] | 0.003a | 0.005 | 0.01 | 0.02 | 0.04 |
   rs3823773 | intron | 0.09 | 0.12 | 0.69 [0.44-1.07] | 0.098 | 0.07 | 0.08 | 0.11 | 0.03 |
   rs736781 | intron | 0.14 | 0.2 | 0.66 [0.46-0.95] | 0.025a | 0.03 | 0.05 | 0.01 | 0.02 |
   rs2893375 | intron | 0.21 | 0.17 | 1.3 [0.94-1.79] | 0.110 | 0.07 | 0.01 | 0.03 | 0.02 |
   rs2529440 | intron | 0.41 | 0.42 | 0.96 [0.74-1.24] | 0.750 | 0.01 | 0.03 | 0.02 | -# |
   rs4720004 | intron | 0.19 | 0.14 | 1.5 [1.07-2.09] | 0.017a | 0.03 | 0.03 | -# | -# |
   rs932272 | intron | 0.39 | 0.39 | 0.98 [0.75-1.28] | 0.887 | 0.76 | -# | -# | -# |
   rs17770244 | intron | 0.06 | 0.06 | 1.11 [0.65-1.89] | 0.704 | -# | -# | -# | -# |