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Figure 4 | BMC Gastroenterology

Figure 4

From: Investigation of innate immunity genes CARD4, CARD8 and CARD15 as germline susceptibility factors for colorectal cancer

Figure 4

Power analysis of the sample used in the present study. The power of an allelic test is plotted as a function of the underlying odds ration of the tested genetic variant. Calculations were performed for a nominal significance level of 0.05 in a two-sided test. The different colors denote the frequency of the minor allele of the respective variant. Clearly, power increased for frequent variants and higher underlying odds. It is evident, that odds ratios above 1.6 should be detectable with a power greater 80% for all allele frequencies. The graph was generated using PS-power [27] and shows the power as a function of the odds ratio (x-axis).

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