Figure 1

Overview of the physical and genetic structure of the CARD4 gene region. The gene is annotated on the genomic minus strand. The physical position of the investigated SNPs and a schematic illustration of the gene structure are shown in the top panel. The coordinates refer to genome assembly build 35. The lower panel gives an overview of the linkage disequilibrium structure of the locus [D'] as generated by Haploview [29]. The LD plots have been generated from the HAPMAP data.