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Table 3 Distribution of genotype frequencies according to IM and HP infection status

From: Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study

Gene polymorphism
(rs number)
Genotype IM- IM+ HP- HP+
     IM- IM+ IM- IM+
ADPRT Val762Ala
(rs1136410)
TT 71 31 33 9 38 22
  TC 117 60 64 24 53 36
  CC 33 16 13 6 20 10
EGF +61A/G
(rs4444903)
AA 22 5 13 1 9 4
  AG 103 55 54 20 49 35
  GG 110 58 50 18 60 40
FR-α 1314A/G
(none)
GG 164 95 74 30 90 65
  GA 74 31 43 12 31 19
  AA 6 1 5 0 1 1
HER2 Ile/Val
(rs1801200)
AA 174 92 87 32 87 60
  AG 60 30 29 8 31 22
  GG 1 1 1 1 0 0
IL1RN 86-bp VNTR
(none)
44 212 101 112 33 100 68
  24 28 18 9 4 19 14
  34 1 2 0 2 1 0
  54 0 1 0 0 0 1
  22 2 2 0 1 2 1
IL-1β -511C/T
(rs16944)
CC 64 35 33 10 31 25
  CT 119 62 63 21 56 41
  TT 48 23 20 10 28 13
IL-10 -819T/C
(rs1800871)
TT 131 55 57 21 74* 34
  TC 78 46 39 15 39 31
  CC 22 16 17 3 5 13
IL-10 -1082A/G
(rs1800896)
AA 207 100 98 37 109 63
  AG 21 14 13 3 8 11
  GG 2 0 2 0 0 0
MMP2 -1306C/T
(rs243865)
CC 178 79 85 28 93 51
  CT 46 22 26 8 20 14
  TT 3 2 2 0 1 2
MTHFR 667C/T
(rs1801133)
CC 132 77 64 23 68 54
  CT 98 42 50 16 48 26
  TT 14 7 8 2 6 5
NQO1 609C/T
(rs1800566)
CC 64* 21 27 10 37* 11
  CT 143 80 78 25 65 55
  TT 28 22 13 4 5 18
TP53 Arg72Pro
(rs1042522)
CC 45 16 22 7 23 9
  CG 126 78 66 23 60 55
  GG 51 26 24 10 27 16
PTPN11 rs2301756
(rs2301756)
GG 175 85 92* 24 83* 61
  GA 58 28 26 16 32 12
  AA 4 2 0 1 4 1
STCH rs12479
(rs12479)
GG 102 58 51 20 51 38
  GA 106 39 52 12 54 27
  AA 22 15 10 8 12 7
STCH rs1882881
(rs1882881)
AA 58 34 24 13 34 21
  AC 123 58 67 15 56 43
  CC 57 31 26 13 31 18
STCH rs2242661
(rs2242661)
AA 69 31 34 12 35 19
  AG 106 46 52 13 54 33
  GG 44 26 22 13 22 13
STCH rs9982492
(rs9982492)
CC 85 45 41 15 44 30
  CT 105 39 53 12 52 27
  TT 28 18 14 9 14 9
SULT1A1 638G/A
(rs9282861)
GG 221 108 112 33 109 75
  GA 16 10 6 6 10 4
  AA 1 0 1 0 0 0
  1. * Bold type denotes significant difference in genotype frequencies