Figure 3
From: Hepatitis B virus inhibition in mice by lentiviral vector mediated short hairpin RNA
Serum HBV antigens levels in HBV shRNA-treated mice. (A) HBsAg levels in NOD SCID mouse sera were significantly reduced after treatment with the shRNA expression lentiviral vectors pWPT-HBV-shRNA-1 and shRNA-2. (B) The levels of HBeAg were significantly reduced by treatment with HBV shRNAs in mice. Inhibition of HBV antigens were specific and lasted at least 7 days (error bars indicate standard errors). The values showed the average of three experiments (means standard deviation). The mean value of empty control was defined as 100%. *P < 0.05 vs. the empty vector group. # P > 0.05 vs. the empty vector group.