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Table 3 Colon ACF number and multiplicity at 6 weeks post-AOM *

From: Lack of efficacy of blueberry in nutritional prevention of azoxymethane-initiated cancers of rat small intestine and colon

 

Male

Female

Number of Small ACF

  

   Control

129.5 ± 15.4

117.6 ± 15.1 a

   10% BB

99.9 ± 8.9

152.8 ± 11.9 b

Interaction between diet and gender

P = 0.016

Number of Large ACF

  

   Control

12.2 ± 2.4

7.1 ± 2.5

   10% BB

8.1 ± 1.7

10.1 ± 2.2

Interaction between diet and gender

NS

Total Number of ACF

  

   Control

141.7 ± 16.7 a

124.7 ± 15.2 a

   10% BB

107.9 ± 10.0 b

162.8 ± 12.8 b

Interaction between diet and gender

P = 0.012

ACF Crypt Multiplicity

  

   Control

2.1 ± 0.1

1.9 ± 0.1

   10% BB

2.0 ± 0.1

1.9 ± 0.1

Interaction between diet and gender

NS

  1. *Small ACF includes those with 1, 2 or 3 crypts; large ACF are those with 4 or more crypts; total ACF = no. small ACF + no. large ACF; ACF crypt multiplicity = no. of crypts per ACF.
  2. a, b within a column represents 0.1 > P > 0.05, student's t-test; also shown are P values for overall interaction between diet and gender as determined by two-way ANOVA.
  3. n = 15 animals per gender for each diet group.
  4. NS: P > 0.1