Table 4 Genotype frequencies for PTPN11 rs2301756 polymorphism, odds ratios (ORs) and 95% confidence intervals (CIs) of gastric atrophy in the H. pylori seropositive subjects (a) and H.pylori infected subjects (b)

643

350 (54.4)

1

Reference

-

127 (19.8)

1

Reference

-

266

131 (49.2)

0.82

0.62–1.10

0.194

38 (14.3)

0.70

0.47–1.04

0.079

28

14 (50.0)

0.84

0.39–1.81

0.650

3 (10.7)

0.56

0.17–1.91

0.356

294

145 (49.3)

0.83

0.62–1.09

0.182

41 (13.9)

0.68

0.46–1.01

0.057

1552

831 (53.5)

1

Reference

-

292 (18.8)

1

Reference

-

322

159 (49.4)

0.85

0.66–1.08

0.097

44 (13.7)

0.67

0.45–0.96

0.015

n

All gastric atrophy (%)

OR ^a

95% CI

P value ^b

Severe gastric atrophy (%)

OR ^a

95% CI

P value ^b

677

383 (56.6)

1

Reference

-

151 (22.3)

1

Reference

-

274

139 (50.7)

0.80

0.60–1.06

0.123

41 (15.0)

0.63

0.43–0.93

0.019

28

14 (50.0)

0.77

0.36–1.67

0.512

3 (10.7)

0.49

0.14–1.67

0.254

302

153 (50.7)

0.80

0.60–1.05

0.106

44 (14.6)

0.62

0.42–0.90

0.012

1628

905 (55.6)

1

Reference

-

343 (21.1)

1

Reference

-

330

167 (50.6)

0.82

0.64–1.05

0.102

47 (14.2)

0.62

0.44–0.87

0.005