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Table 3 Adjusted OR for cancers at upper, middle and lower third of the esophagus associated with COX-2 -1195G/A polymorphism.

From: Polymorphism in COX-2 modifies the inverse association between Helicobacter pyloriseropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study

COX-2 polymorphism Controls Location of ESCC Total cases
   Upper + Middle Lower   
  No. (%) No. (%). AOR1 (95% CI) No. (%). AOR1 (95% CI) No. (%). AOR1 (95% CI)
GG 50 (26) 23 (19) 1.0 16 (28) 1.0 39 (22) 1.0
AG 103 (53) 59 (48) 1.7 (0.7 – 4.0) 21 (36) 0.9 (0.3 – 2.3) 80 (44) 1.2 (0.6 – 2.4)
AA 41 (21) 40 (33) 2.0 (0.7 – 5.2) 21 (36) 2.3 (0.8 – 6.7) 61 (34) 2.3 (1.0 – 5.2)
p for H-W2 0.471       
GG+AG 153 (79) 82 (67) 1.0 37 (64) 1.0 119 (66) 1.0
AA 41 (21) 40 (33) 1.4 (0.7 – 2.9) 21 (36) 2.5 (1.0 – 6.1) 61 (34) 2.0 (1.1 – 3.9)
  1. 1 Odds ratios were adjusted for the covariates (age, gender, education level, pack-years of cigarette smoking and of betel quid chewing, and drink-years of alcohol drinking) listed in Table 1.
  2. 2 p value for Hardy-Weinberg equilibrium test.