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Table 3 Adjusted OR for cancers at upper, middle and lower third of the esophagus associated with COX-2 -1195G/A polymorphism.

From: Polymorphism in COX-2 modifies the inverse association between Helicobacter pyloriseropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study

COX-2 polymorphism Controls Location of ESCC Total cases
   Upper + Middle Lower   
  No.
(%)
No.
(%).
AOR1
(95% CI)
No.
(%).
AOR1
(95% CI)
No.
(%).
AOR1
(95% CI)
GG 50
(26)
23
(19)
1.0 16
(28)
1.0 39
(22)
1.0
AG 103
(53)
59
(48)
1.7
(0.7 – 4.0)
21
(36)
0.9
(0.3 – 2.3)
80
(44)
1.2
(0.6 – 2.4)
AA 41
(21)
40
(33)
2.0
(0.7 – 5.2)
21
(36)
2.3
(0.8 – 6.7)
61
(34)
2.3
(1.0 – 5.2)
p for H-W2 0.471       
GG+AG 153
(79)
82
(67)
1.0 37
(64)
1.0 119
(66)
1.0
AA 41
(21)
40
(33)
1.4
(0.7 – 2.9)
21
(36)
2.5
(1.0 – 6.1)
61
(34)
2.0
(1.1 – 3.9)
  1. 1 Odds ratios were adjusted for the covariates (age, gender, education level, pack-years of cigarette smoking and of betel quid chewing, and drink-years of alcohol drinking) listed in Table 1.
  2. 2 p value for Hardy-Weinberg equilibrium test.