Polymorphism in COX-2 modifies the inverse association between Helicobacter pylori seropositivity and esophageal squamous cell carcinoma risk in Taiwan: a case control study

Table 2 Adjusted OR for cancers at upper, middle and lower third of the esophagus associated with seropositivity of H. pylori

H. pylori infection	Controls	Location of ESCC				Total cases
		Upper + Middle		lower
	No. (%)	No. (%)	AOR¹ (95% CI)	No. (%)	AOR¹ (95% CI)	No. (%)	AOR¹ (95% CI)
Negative	92 (47)	76 (62)	1.0	38 (66)	1.0	114 (63)	1.0
Positive	102 (53)	46 (38)	0.6 (0.3 – 1.1)	20 (34)	0.5 (0.2 – 1.0)	66 (37)	0.5 (0.3 – 0.9)

¹ Odds ratios were adjusted for the covariates (age, gender, education level, pack-years of cigarette smoking and of betel quid chewing, and drink-years of alcohol drinking) listed in Table 1.