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Table 1 Effects of flovoksamine (FLU) and ranitidine (RAN) on indomethacin (IND) induced ulcers in rats.

From: Antiulcer activity of fluvoxamine in rats and its effect on oxidant and antioxidant parameters in stomach tissue

Drugs Dose
(mg/kg)
Number of animals Ulcer area (mm2) Antiulcer effect (%) P
FLU 25     < 0.05
+   6 15.3 ± 1.5 48.5  
IND 25     
FLU 50     < 0.02
+   6 9.7 ± 0.9 67.5  
IND 25     
FLU 100     < 0.01
+   6 5.3 ± 0.4 82.1  
IND 25     
FLU 200     < 0.001
+   6 1.2 ± 0.02 96.1  
IND 25     
RAN 50     < 0.001
+   6 4.0 ± 0.6 86.5  
IND 25     
Indomethacin (Control) 25 6 29.7 ± 2.6 - -