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Table 1 Comparison of Characteristics between ESCC cases and controls (P value: Mann-Whitney U test; *chi square test; **Fisher's exact test).

From: Macroscopic extent of gastric mucosal atrophy: increased risk factor for esophageal squamous cell carcinoma in Japan

 

ESCC cases

(N = 253)

Controls

(N = 253)

p-value

Patients profiles

   

Male/Female

225/28

225/28

>0.9999

Age (median; range)

65; 38–86

65; 38–86

>0.9999

BMI (median; range)

20.9; 14.8–30.8

22.8; 14.5–33.1

<0.0001

Current regular drinker

210 (83.0%)

142 (56.1%)

<0.0001*

Current smoker

Endoscopic findings

205 (81.0%)

133 (52.6%)

<0.0001*

GMA Open-type 2, 3

164 (64.8%)

127 (50.2%)

0.0009*

Hiatal hernia

60 (23.7%)

74 (29.2%)

0.1584*

Erosive esophagitis

   

Total (LA-A to D)

13 (5.1%)

64 (25.3%)

<0.0001*

Mild (LA-A, B)

12 (4.7%)

59 (23.3%)

<0.0001*

Severe (LA-C, D)

1 (0.4%)

5 (2.0%)

0.2160**

Barrett's epithelium

80 (31.6)

114 (45.1%)

0.0019*

  1. BMI = body mass index; GMA = gastric mucosal atrophy