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Table 1 Reported incidences of peptic ulcer complications (cases per 100000 inhabitants per year).

From: Decreasing incidence of peptic ulcer complications after the introduction of the proton pump inhibitors, a study of the Swedish population from 1974–2002

Country (ref) Period Reported incidences   Comment Studied variable
   perforation Bleeding   
Norway (18) 1935–1990 About 10   Report birth cohort specific risks for perforation Admittance rates
USA (44) 1956–1985 10-5 7-4 Relatively stable incidence of emergency operations for PUC Emergency operations
England and
Wales (13)
1958–1962
1979–1982
   Increasing incidence of PUC* and NSAID use in elderly ♀ National register
Scotland (13) 1958–1962
1979–1982
   Increasing incidence of PUC* and NSAID use in elderly ♀ National register
USA (45) 1974–1976
1984-1984
No rate per 100000 inhab No rate per 100000 inhab 13% increase in perforations and 7% increase in bleedings after H2-rec blocker introduction Cases operated
Poland (11) 1977–1996 No rate per 100000 inhab   Constant number/year, increasing % elderly women, increasing mean age Cases operated
Hong-Kong (19) 1979–1985 14–18    Operating room
logbooks
New South Wales (19) 1979–1985 3–4    Diagnosis reported to dept of heath
Finland (12,46) 1972–1987
1987–1999
4–5
5–7
3–4 Increasingly more ♀, increasing mean age Cases operated, national register
Sweden (1) 1974–92 2–11   Significant decrease in incidence Patients records
Denmark (20) 1974–1984 4–10 5–10 No significant difference before/after H2-receptor blockers Cases operated
Finland (17) 1977–1989 2–8 3–9 No significant difference before/after H2-receptor blockers Cases operated
Finland (15) 1979-85-00 3-6-4   No significant difference before/after H2-receptor blockers or PPI Patients records
UK (10) 1989–99 ♂ 10–11
♀ 7-7
27–31
14–16
  Admittance rates
UK (47) 1996–98 ♂ 5
♀ 4
  Only duodenal perforations, increasing mean age in ♀ Patients records
Germany (23) 1989–90
1999-00
  51
49
Patients older and more NSAID use in the later period Prospective
  1. *PUC = peptic ulcer complications