Table 1 Reported incidences of peptic ulcer complications (cases per 100000 inhabitants per year).

Norway (18)

1935–1990

About 10

Report birth cohort specific risks for perforation

Admittance rates

USA (44)

1956–1985

10-5

7-4

Relatively stable incidence of emergency operations for PUC

Emergency operations

England and

Wales (13)

1958–1962

1979–1982

Increasing incidence of PUC* and NSAID use in elderly ♀

National register

Scotland (13)

1958–1962

1979–1982

Increasing incidence of PUC* and NSAID use in elderly ♀

National register

USA (45)

1974–1976

1984-1984

No rate per 100000 inhab

No rate per 100000 inhab

13% increase in perforations and 7% increase in bleedings after H2-rec blocker introduction

Cases operated

Poland (11)

1977–1996

No rate per 100000 inhab

Constant number/year, increasing % elderly women, increasing mean age

Cases operated

Hong-Kong (19)

1979–1985

14–18

Operating room

logbooks

New South Wales (19)

1979–1985

3–4

Diagnosis reported to dept of heath

Finland (12,46)

1972–1987

1987–1999

4–5

5–7

3–4

Increasingly more ♀, increasing mean age

Cases operated, national register

Sweden (1)

1974–92

2–11

Significant decrease in incidence

Patients records

Denmark (20)

1974–1984

4–10

5–10

No significant difference before/after H2-receptor blockers

Cases operated

Finland (17)

1977–1989

2–8

3–9

No significant difference before/after H2-receptor blockers

Cases operated

Finland (15)

1979-85-00

3-6-4

No significant difference before/after H2-receptor blockers or PPI

Patients records

UK (10)

1989–99

♂ 10–11

♀ 7-7

27–31

14–16

Admittance rates

UK (47)

1996–98

♂ 5

♀ 4

Only duodenal perforations, increasing mean age in ♀

Patients records

Germany (23)

1989–90

1999-00

51

49

Patients older and more NSAID use in the later period

Prospective