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Table 5 Clinical characteristics of individuals with VA and inflammation – patient chart review.

From: Validation study of villous atrophy and small intestinal inflammation in Swedish biopsy registers

 

Villous atrophy;

N= 118

Inflammation;

N= 39

Background data

  

Females

72 (61)

16 (41)

Median age at first biopsy; range (years)

42; 1–86

53; 1–84

Median follow-up; range (years)

7; 0–24

6; 0–17

Heredity

  

Reported heredity for CD

14 (12)

2 (5)

Reported heredity for type 1 diabetes

3 (3)

0 (0)

Other diseases

  

Diabetes Mellitus, type 1

5 (4)

1 (3)

Dermatitis herpetiformis

6 (5)

0 (0)

Other autoimmune disease

11 (9)

8 (21)

Symptoms

  

Any gastrointestinal symptom*

93 (79)

25 (64)

Diarrhea

42 (36)

7 (18)

Anemia

41 (35)

12 (31)

Weight loss/growth failure

34 (29)

3 (8)

Abdominal pain

22 (19)

9 (23)

Vomiting or nausea

15 (13)

6 (15)

Constipation

12 (10)

1 (3)

Fatigue

9 (8)

3 (8)

Laboratory data

  

Iron-deficiency

32 (27)

5 (13)

Folic acid deficiency

26 (22)

2 (5)

B12-deficiency

16 (14)

1 (3)

Thrombocytes, increased

15 (13)

4 (10)

Low albumin

12 (10)

7 (18)

Erythrocyte sedimentation rate, increased

9 (8)

3 (8)

Liver enzymes, increased

9 (8)

4 (10)

Biopsy report

  

Original biopsy report could be examined through

patient chart reviews

98 (83)

33 (85)

Clinical data (about the patient) is described in the

biopsy referral letter (to the pathologist)#

90 (92)

28 (85)

Macroscopic appearance of the intestine is described

in the referral letter#

39 (40)

14 (42)

  1. Percentages are given within brackets. Although, the diagnosis CD was evaluated in 121 individuals, patient chart data were only available in 118 (98%).
  2. *Weight loss was included among "any GI symptom". Also reflux symptoms (not listed above) were included among "any GI symptoms".
  3. #Based on 98 and 33 biopsy reports respectively.