From: Validation study of villous atrophy and small intestinal inflammation in Swedish biopsy registers
 | Villous atrophy; N= 118 | Inflammation; N= 39 |
---|---|---|
Background data | Â | Â |
Females | 72 (61) | 16 (41) |
Median age at first biopsy; range (years) | 42; 1–86 | 53; 1–84 |
Median follow-up; range (years) | 7; 0–24 | 6; 0–17 |
Heredity | Â | Â |
Reported heredity for CD | 14 (12) | 2 (5) |
Reported heredity for type 1 diabetes | 3 (3) | 0 (0) |
Other diseases | Â | Â |
Diabetes Mellitus, type 1 | 5 (4) | 1 (3) |
Dermatitis herpetiformis | 6 (5) | 0 (0) |
Other autoimmune disease | 11 (9) | 8 (21) |
Symptoms | Â | Â |
Any gastrointestinal symptom* | 93 (79) | 25 (64) |
Diarrhea | 42 (36) | 7 (18) |
Anemia | 41 (35) | 12 (31) |
Weight loss/growth failure | 34 (29) | 3 (8) |
Abdominal pain | 22 (19) | 9 (23) |
Vomiting or nausea | 15 (13) | 6 (15) |
Constipation | 12 (10) | 1 (3) |
Fatigue | 9 (8) | 3 (8) |
Laboratory data | Â | Â |
Iron-deficiency | 32 (27) | 5 (13) |
Folic acid deficiency | 26 (22) | 2 (5) |
B12-deficiency | 16 (14) | 1 (3) |
Thrombocytes, increased | 15 (13) | 4 (10) |
Low albumin | 12 (10) | 7 (18) |
Erythrocyte sedimentation rate, increased | 9 (8) | 3 (8) |
Liver enzymes, increased | 9 (8) | 4 (10) |
Biopsy report | Â | Â |
Original biopsy report could be examined through patient chart reviews | 98 (83) | 33 (85) |
Clinical data (about the patient) is described in the biopsy referral letter (to the pathologist)# | 90 (92) | 28 (85) |
Macroscopic appearance of the intestine is described in the referral letter# | 39 (40) | 14 (42) |