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Table 3 Subgroup analysis of the effect of corticosteroid prophylaxis of post-ERCP pancreatitis in clinical trials

From: Meta-analysis of prophylactic corticosteroid use in post-ERCP pancreatitis

      Heterogeneity
Variable Patients Pooled OR (95% CI) Z p χ2 d.f. p
  PEP
Jadad score        
   ≥ 3 2247 1.10 (0.85, 1.43) 0.72 0.47 8.11 4 0.09
   ≤ 2 385 1.31 (0.70, 2.46) 0.85 0.39 0.28 1 0.59
Setting        
   Single centre 1034 1.04 (0.66, 1.64) 0.16 0.87 4.75 3 0.19
   Multicentre 1598 1.17 (0.88, 1.56) 1.07 0.29 3.84 2 0.15
  Severe PEP
Jadad score        
   ≥ 3 1872 1.35 (0.47, 3.91) 0.55 0.58 0.14 1 0.71
   ≤ 2 385 1.98 (0.62, 6.34) 1.14 0.25 1.12 1 0.29
Setting        
   Single centre 914 1.99 (0.70, 5.67) 1.28 0.20 1.12 2 0.57
   Multicentre 1343 1.21 (0.37, 4.00) 0.32 0.75 NA NA NA
  Post-ERCP hyperamylasemia
Jadad score        
   ≥ 3 228 0.87 (0.52, 1.46) 0.53 0.60 NA NA NA
   ≤ 2 184 1.24 (0.37, 4.22) 0.35 0.73 NA NA NA
Setting        
   Single centre 184 1.24 (0.37, 4.22) 0.35 0.73 NA NA NA
   Multicentre 228 0.87 (0.52, 1.46) 0.53 0.60 NA NA NA
  1. NA = not applicable