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Table 2 Comparison of clinicopathological findings by PTEN expression

From: Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

   PTEN expression
   Group S (n = 17) Group W (n = 52) pvalue
Gender M/F 10/7 30/22 N.S.
Age Year 60.3 ± 9.7 60.9 ± 10.1 N.S.
TNM stage I/II/III/IV 0/6/7/4 0/6/16/30 < 0.01a
Tumour site C/R 11/6 34/18 N.S.
LN mets Yes/No 8/9 39/13 < 0.05a
Differentiation w/mod/por 10/7/0 27/23/2 N.S.
Liver mets Sync/Meta 4/13 19/33 N.S.
No. of liver mets Solo/Multi 9/8 29/23 N.S.
5-year survival (%) 64.4 12.7 < 0.05b
  1. LN, lymph node; mets, metastasis; M, male; F, female; C, colon; R, rectum; w, well differentiated adenocarcinoma; mod, moderately differentiated adenocarcinoma; por, poorly differentiated adenocarcinoma; Sync, synchronous metastasis; Meta, metachronous metastasis, Solo, solitary metastasis; Multi, multiple metastases; N.S., not significant. The a p-values were obtained using the Mann-Whiteny U test. The b p-values were obtained using Kaplan-Meier survival curves based on PTEN expression tested with the Wilcoxon test. Values of age are given mean ± s.d. N.S., not significant.