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Table 2 Comparison of clinicopathological findings by PTEN expression

From: Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival

  

PTEN expression

  

Group S (n = 17)

Group W (n = 52)

pvalue

Gender

M/F

10/7

30/22

N.S.

Age

Year

60.3 ± 9.7

60.9 ± 10.1

N.S.

TNM stage

I/II/III/IV

0/6/7/4

0/6/16/30

< 0.01a

Tumour site

C/R

11/6

34/18

N.S.

LN mets

Yes/No

8/9

39/13

< 0.05a

Differentiation

w/mod/por

10/7/0

27/23/2

N.S.

Liver mets

Sync/Meta

4/13

19/33

N.S.

No. of liver mets

Solo/Multi

9/8

29/23

N.S.

5-year survival

(%)

64.4

12.7

< 0.05b

  1. LN, lymph node; mets, metastasis; M, male; F, female; C, colon; R, rectum; w, well differentiated adenocarcinoma; mod, moderately differentiated adenocarcinoma; por, poorly differentiated adenocarcinoma; Sync, synchronous metastasis; Meta, metachronous metastasis, Solo, solitary metastasis; Multi, multiple metastases; N.S., not significant. The a p-values were obtained using the Mann-Whiteny U test. The b p-values were obtained using Kaplan-Meier survival curves based on PTEN expression tested with the Wilcoxon test. Values of age are given mean ± s.d. N.S., not significant.
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BMC Gastroenterology

ISSN: 1471-230X

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