TY - JOUR AU - Sawai, Hirozumi AU - Yasuda, Akira AU - Ochi, Nobuo AU - Ma, Jiachi AU - Matsuo, Yoichi AU - Wakasugi, Takehiro AU - Takahashi, Hiroki AU - Funahashi, Hitoshi AU - Sato, Mikinori AU - Takeyama, Hiromitsu PY - 2008 DA - 2008/11/26 TI - Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival JO - BMC Gastroenterology SP - 56 VL - 8 IS - 1 AB - The tumour suppressor phosphatase and tensin homolog (PTEN) is an important negative regulator of cell-survival signaling. To evaluate the correlation between PTEN expression and clinicopathological characteristics of colorectal cancer patients with and without liver metastases, we investigated PTEN expression in primary colorectal cancer and colorectal cancer liver metastases. SN - 1471-230X UR - https://doi.org/10.1186/1471-230X-8-56 DO - 10.1186/1471-230X-8-56 ID - Sawai2008 ER -