Table 3 Univariate analysis: Clinical and biochemical factors related to bleeding lesions on endoscopy
Endoscopic lesions Identified (n = 51) | No endoscopic lesions Identified (n = 44) | Odds ratio | 95%CI | P value | |
|---|---|---|---|---|---|
Clinical variables | |||||
Age (yrs) Mean (SD) | 57.3(14.5) | 49.3(17.4) | 1.04 | 1.01 – 1.07 | <0.001 |
Age ≥ 55 yrs † | 30(58.8%) | 10 (22.7%) | 4.8 | 1.9 – 11.9 | <0.001 |
NSAID users †† | 16(31.4%) | 06(13.6%) | 2.8 | 1.0 – 8.2 | 0.04 |
Hx of Weight loss ††† | 16(31.4%) | 13(29.5%) | 1.0 | 0.4 – 2.6 | 0.84 |
Hx of Fatigue/Lethargy ¶ | 13(25.5%) | 05(11.4%) | 2.6 | 0.8 – 8.2 | 0.11 |
Prior Hx of IDA therapy ¶¶ | 07(13.7%) | 02(4.5%) | 3.3 | 0.6 – 0.9 | 0.14 |
Biochemical Variables | |||||
Hb≤ (gm/dl) Mean (SD) | 6.6(1.9) | 7.5(2.1) | 0.8 | 0.6 – 0.9 | 0.04 |
Hb ≤ 9 gm/dl ‡ | 46(90.2%) | 29(65.9%) | 4.7 | 1.5 – 14.4 | 0.004 |
MCV (fl) Mean (SD) | 60.3(5.6) | 62.2(5.6) | 0.9 | 0.8 – 1.0 | 0.1 |
MCV ≤ 60 fl ‡‡ | 32(62.7%) | 14(31.8%) | 3.6 | 1.5 – 8.4 | 0.003 |
Serum Iron (μg/dl) Mean(SD) | 10.5(6.8) | 12.5(5.1) | 0.9 | 0.8 – 1.0 0.13 | |
Serum Iron ≤ 10 (μg/dl) * | 31(60%) | 19(43.0%) | 2.0 | 0.8 – 4.6 0.08 | |
TIBC (μg/dl) Mean (SD) | 396(88) | 379(79) | 1.0 | 0.9 – 1.0 0.33 | |
Transferrin saturation (%) Mean (SD) | 4.4(4.4) | 4.1(4.1) | 1.0 | 0.9 – 1.2 0.47 | |
Ferritin (ng/ml) Mean (SD) | 6.3(4.2) | 5.8(3.3) | 1.03 | 0.9 – 1.1 0.54 | |
Ferritin ≤ 5 (ng/ml) ** | 28(54.9%) | 18(40.9%) | 1.75 | 0.7 – 3.9 0.17 | |
FOB (Positive) *** | 27(52.9%) | 03(6.8%) | 15.3 | 4.2 – 56.1 | <0.001 |