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Table 4 Comparing age stratified cohorts of male CD patients vs. healthy male controls

From: Bones and Crohn's: Estradiol deficiency in men with Crohn's disease is not associated with reduced bone mineral density

 

< 30 years

 

30 – 45 years

 

> 45 years

 
 

Patients

(n = 32)

Controls

(n = 31)

p

Patients

(n = 48)

Controls

(n = 36)

p

Patients

(n = 31)

Controls

(n = 32)

p

Testosterone (nmol/l)

20.1

(8.8 – 40.6)

23.0

(11.2 – 33.9)

 

18.7

(9.6 – 48.0)

21.7

(10.4 – 39.6)

0.025

15.5

(11 – 26.2)

19.4

(8.7 – 32.8)

< 0.01

SHBG (nmol/l)

19,3

(6.9 – 47.3)

32

(8.2 – 46.9)

<0.0025

21.4

(11.5 – 69.3)

28.3

(6.9 – 70.5)

 

24.1

(12.2 – 52.7)

37.8

(12.7 – 70.4)

< 0.01

FAI

100

(34 – 100)

78

(39 – 163)

<0.025

86

(18 – 232)

65.5

(28 – 208)

 

67

(26 – 146)

52.5

(27 – 168)

 

DHT (pg/ml)

278

(66 – 562)

310

(95 – 616)

<0.05

263

(67 – 750)

266

(103 – 712)

 

262

(110 – 750)

218

(80 – 798)

 

Estradiol (pg/ml)

25.8

(12.2 – 39.6)

37.5

(29.8 – 57.4)

<0.001

24.8

(9.4 – 46.6)

32.1

(20.1 – 45.6)

<0.001

26.7

(18.4 – 47.8)

30.9

(18.7 – 52.6)

<0.0025

FEI

49

(15 – 140)

53

(25 – 136)

 

40

(9 – 93)

45

(15 – 158)

 

39

(14 – 143)

36

(11 – 96)

 

Osteocalcin (ng/ml)

3.4

(1.0 – 12.8)

4.5

(1.0 – 14.9)

 

2.8

(0.5 – 10.1)

2.4

(0.6 – 6.0)

 

2.6

(0.3 – 9.5)

2.1

(0.3 – 5.4)

 

ICTP (μg/l)

4.4

(2.1 – 11.7)

3.9

(2.0 – 7.1)

<0.05

3.6

(1.7 – 20.8)

3.1

(2.2 – 4.7)

<0.0025

3.6

(2.3 – 6.0)

3.2

(2.0 – 4.8)

<0.025

T-score

(lumbar spine)

-1.72

(-3.8 – +0.05)

  

-2.02

(-3.9 – +0.84)

  

-2.11

(-3.94 – +0.28)

  
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BMC Gastroenterology

ISSN: 1471-230X

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