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Table 3 Demographic and clinical characteristics in patients with cirrhosis due to alcoholic liver disease, hepatitis C, and cholestatic liver disease

From: Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional study

 

Alcoholic liver cirrhosis (n = 55)

Hepatitis C cirrhosis (n = 32)

Cholestatic cirrhosis (n = 29)

Age

60 (8) *

54 (7)

54 (14)

Female/Male

12/43 (22%/78%)

9/23 (28%/72%)

9/20 (31%/69%)

Outpatients/inpatients

42/13 (76%/24%)

27/5 (84%/16%)

25/4 (86%/14%)

Previous variceal bleeding

15 (27%)

7 (22%)

8 (28%)

Esophageal and/or fundic varices

37 (67%)

21 (66%)

24 (83%)

Ascites

31 (56%)*

10 (31%)

9 (31%)

Hepatocellular carcinoma

6 (11%)

9 (28%)*

1 (3.4%)

Number connection test A

   

   Mean (SD) (sec)

68 (51)

52 (33)

50 (44)

   Above 3 SDa

10 (18%)

2 (6%)

3 (10%)

Number Connection test B

   

   Mean (SD) (sec)

165 (87)

141 (83)

118 (69)

   Above 3 SDa

13 (24%)

5 (16%)

4 (14%)

Overt hepatic encephalopathy

15 (27%)

6 (19%)

4 (14%)

(West-Haven)b

   

   Grade I

14 (25.5%)

6 (19%)

3 (10.5%)

   Grade II

1 (2%)

0

1 (3.5%)

Minimal hepatic

4 (7%)

2 (6%)

2 (7%)

encephalopathyc

19 (34%)

8 (25%)

6 (21%)

Hepatic encephalopathy

   

(minimal or overt)

   

Fasting plasma ammonium ion (μmol/l)

50 (26)

51 (35)

52 (21)

MELD score

14.9 (7.2)

12.6 (5)

14.3 (5.4)

Child-Pugh score

9 (2.6)

8.2 (2.2)

8.8 (2)

Diabetes mellitus

20 (36%)

11 (34%)

3 (10%)*

  1. Data are presented as mean (SD) or n (%) as appropriate
  2. a Compared to age-corrected normal values from the general population
  3. b Overt hepatic encephalopathy according to West-Haven criteria: none with grade III or IV
  4. c Defined as absence of overt hepatic encephalopathy and number connection test A > 3SD and/or number connection test B > 3SD
  5. For comparisons of continuous variables if one-Way ANOVA was significant (p < 0.05), the post-hoc Bonferroni test was used for comparisons among different groups.
  6. For comparisons of if the chi-square test was significant (p < 0.05) when data from all groups were tested, the chi-square test was used for post-hoc analysis among different groups
  7. *p < 0.05 compared to the other two groups