Type and etiology of liver cirrhosis are not related to the presence of hepatic encephalopathy or health-related quality of life: a cross-sectional study

Table 1 Demographic and clinical characteristics in patients with hepatocellular and cholestatic liver cirrhosis

	Hepatocellular cirrhosis (n = 127)	Cholestatic cirrhosis (n = 29)	p-value
Age	56 (11)	54 (14)	0.496
Female/Male	33/94 (26%/74%)	9/20 (31%/69%)	0.580
Outpatients/inpatients	104/23 (82%/18%)	25/4 (86%/14%)	0.579
Previous variceal bleeding	37 (29%)	8 (28%)	0.953
Esophageal and/or fundic varices	88 (69%)	24 (83%)	0.139
Ascites	55 (43%)	9 (31%)	0.225
Hepatocellular carcinoma	22 (17%)	1 (3.4%)	0.06
Number connection test A
Mean (SD) (sec)	61 (44)	50 (44)	0.258
Above 3 SD^a	17 (13%)	3 (10%)	0.567
Number Connection test B
Mean (SD) (sec)	148 (82)	118 (69)	0.08
Above 3 SD^a	26 (20%)	4 (14%)	0.303
Overt hepatic encephalopathy	32 (25%)	4 (14%)	0.216
(West-Haven)^b
Grade I	30 (23.5%)	3 (10.5%)
Grade II	2 (1.5%)	1 (3.5%)
Minimal hepatic encephalopathy^c	9 (7%)	2 (7%)	0.93
Hepatic encephalopathy	41 (32%)	6 (21%)	0.175
(minimal or overt)
Fasting plasma ammonium ion (μmol/l)	58 (37)	52 (21)	0.292
MELD score	13.7 (6.2)	14.3 (5.4)	0.645
Child-Pugh score	8.6 (2.4)	8.8 (2)	0.752
Diabetes Mellitus	44 (35%)	3 (10%)	0.01

Data are presented as mean (SD) or n (%) as appropriate
^a Compared to age-corrected normal values from the general population
^b Overt hepatic encephalopathy according to West-Haven criteria: none with grade III or IV
^c Defined as absence of overt hepatic encephalopathy and number connection test A > 3SD and/or number connection test B > 3SD

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