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Table 1 Studies of the natural progression of gallblader polyps during follow up of patients and/or subjects

From: Ultrasonographically detected gallbladder polyps: A reason for concern? A seven-year follow-up study

Author Year Country Population n Method Follow-up Period Patients undergoing surgery Changes in polyp diameter during the observation period
       N   Reduction Disappearance Increase Unchanged
Eelkema 1962 USA Patients 113 Cholecystography 15 years       
Moriguchi 1996 Japan Outpatients 109 Ultrasound 5 years 4 No carcinoma 1.9% 1.9% 11.7% 84.5%
Shinkai 1988 Japan Patients 60 Ultrasound Average 22 months 9 No carcinoma No statistically significant change No statistically significant change No statistically significant change No statistically significant change
Heyder 1990 Germany Patients: abdominal screening in a surgical population 92 Ultrasound Average 9 months 2 No carcinoma No data 13% 6,5% No data
Collett 1998 New Zealand Diabetics and healthy controls 564 Ultrasound 2 years – 30 patients 5 years – 22 patients 0 No surgery No data No data No data No data
Sugiyama 2000 Japan Surgical patients 125 Ultrasound/Endo-ultrasound Average 2.6 years 3 No carcinoma 4% 1.6% 7.2% 87.2%
Csendes 2001 Chile Surgical patients with dyspeptic symptoms or routine examination 98 Ultrasound Average 5.9 years Range 24–144 months 14 No carcinoma 2%1/2 7% 18%1/210% 5% 3 53%1/2 72%
  1. 1 after 8 years; 2 after 12 years; 3 after 4 years