Table 4 Comparison between various quantitative phenotypes in groups of NAFLD patients with different SNP genotypes at rs2290602
| Â | GG | GT+TT | p value | GG+GT | TT | p value |
|---|---|---|---|---|---|---|
N | 14 | 101 | Â | 80 | 35 | Â |
Age (years) | 48.5 + 18.5 | 49.5 + 14.7 | 0.8303 | 48.4 + 14.4 | 51.7 + 16.4 | 0.2913 |
BMI (kg/m2) | 27.3 + 7.2 | 27.2 + 4.8 | 0.9194 | 27.0 + 5.1 | 27.6 + 4.9 | 0.5581 |
FBS (mg/dl) | 118.5 + 26.3 | 117.3 + 32.9 | 0.8929 | 116.8 + 32.0 | 118.7 + 32.8 | 0.7791 |
IRI (ul/ml) | 13.6 + 6.2 | 13.7 + 8.9 | 0.9778 | 12.9 + 6.9 | 15.4 + 11.6 | 0.1865 |
HbA1c (%) | 5.39 + 1.26 | 5.88 + 1.26 | 0.1890 | 5.83 + 1.28 | 5.80 + 1.23 | 0.9138 |
Total cholesterol (mg/dl) | 219.1 + 35.7 | 213.1 + 39.3 | 0.6017 | 214.7 + 39.5 | 211.6 + 37.5 | 0.6978 |
HDL cholesterol (mg/dl) | 50.6 + 10.0 | 53.3 + 22.0 | 0.6709 | 51.2 + 16.2 | 57.0 + 29.1 | 0.1800 |
Triglycerides (mg/dl) | 144.9 + 53.7 | 172.1 + 116.4 | 0.4102 | 159.1 + 70.4 | 192.2 + 172.3 | 0.1469 |
AST (U/ml) | 35.0 + 12.2 | 45.8 + 27.5 | 0.1660 | 40.4 + 21.3 | 54.5 + 34.1 | 0.0085 |
ALT (U/ml) | 50.4 + 27.2 | 73.4 + 55.7 | 0.1462 | 62.7 + 37.7 | 89.9 + 76.9 | 0.0127 |
VFA (cm2) | 129.3 + 32.9 | 135.8 + 50.0 | 0.7585 | 135.4 + 47.4 | 134.9 + 51.3 | 0.9703 |
SFA (cm2) | 274.6 + 148.9 | 229.4 + 116.8 | 0.3821 | 235.4 + 123.8 | 230.4 + 114.2 | 0.8709 |