Table 2 Genotype frequencies and association tests of SNPs PPARGC1A gene using NAFLD and control

11

12

22

11

12

22

χ²

P-value

OR ^a (95% CI)

χ²

P-value

OR^a (95% CI)

χ²

P-value

OR^a (95% CI)

rs3774902

Intron 1 +745

T/C

46

49

19

207

170

63

1.6

0.2008

0.82 (0.61 – 1.11)

1.6

0.2010

0.76 (0.50 – 1.16)

0.4

0.52917

0.84 (0.48 – 1.46)

rs2970871

Intron 1 +945

A/G

31

64

19

121

212

107

1.0

0.3225

1.16 (0.87 – 1.55)

0.0

0.9478

0.98 (0.62 – 1.56)

3.0

0.08241

1.61 (0.94 – 2.75)

rs2970876

Intron 1 +2908

C/T

38

55

22

109

226

102

2.8

0.0964

1.28 (0.96 – 1.72)

3.1

0.0804

1.49 (0.95 – 2.32)

0.9

0.33573

1.29 (0.77 – 2.15)

rs2290604

Intron 4 +848

A/G

77

33

3

261

159

21

3.2

0.0716

1.42 (0.97 – 2.07)

3.0

0.0815

1.48 (0.95 – 2.29)

1.0

0.32629

1.83 (0.54 – 6.26)

rs3774907

Intron 5 +161

T/C

75

35

3

280

138

21

0.6

0.4292

1.16 (0.80 – 1.69)

0.3

0.6083

1.12 (0.72 – 1.73)

1.0

0.32239

1.84 (0.54 – 6.29)

rs3774908

Intron 5 +1089

T/C

79

33

3

261

158

21

3.6

0.0580

1.44 (0.99 – 2.10)

3.4

0.0661

1.51 (0.97 – 2.33)

1.0

0.30970

1.87 (0.55 – 6.39)

rs2290603

Intron 5 +3590

A/G

75

35

4

264

154

19

1.0

0.3075

1.21 (0.84 – 1.75)

1.1

0.2933

1.26 (0.82 – 1.94)

0.2

0.68996

1.25 (0.42 – 3.75)

rs2290602

Intron 7 +171

T/G

34

67

13

99

222

113

8.5

0.0036

1.55 (1.15 – 2.08)

2.4

0.1201

1.44 (0.91 – 2.28)

10.9

0.00095

2.73 (1.48 – 5.06)

rs2970849

Intron 7 +8096

A/G

68

42

5

232

173

34

2.2

0.1385

1.30 (0.92 – 1.82)

1.4

0.2287

1.29 (0.85 – 1.96)

1.6

0.20492

1.85 (0.71 – 4.83)

rs2932968

Intron 7 +8494

T/C

74

36

4

262

157

21

1.2

0.2809

1.22 (0.85 – 1.76)

1.1

0.2959

1.26 (0.82 – 1.93)

0.3

0.56233

1.38 (0.46 – 4.10)

rs3755863

Exon 8 +707 (T/T)

G/A

32

60

23

82

222

135

7.3

0.0070

1.49 (1.11 – 2.00)

4.7

0.0308

1.68 (1.05 – 2.69)

5.2

0.02301

1.78 (1.08 – 2.93)

rs3736265

Exon 9 +42 (M/T)

A/G

81

30

3

261

158

20

5.0

0.0259

1.55 (1.05 – 2.29)

5.2

0.0231

1.67 (1.07 – 2.62)

0.8

0.35922

1.77 (0.52 – 6.05)

rs3774920

Intron 10 +1732

A/G

79

32

3

263

157

21

3.8

0.0528

1.46 (0.99 – 2.14)

3.6

0.0587

1.53 (0.98 – 2.37)

1.0

0.31886

1.85 (0.54 – 6.31)

rs768695

Intron 12 +4535

T/C

69

35

9

229

184

27

1.2

0.2737

1.21 (0.86 – 1.70)

2.9

0.0863

1.44 (0.95 – 2.20)

0.5

0.48225

0.76 (0.34 – 1.66)

rs3774923

Exon 13 +2485

A/G

82

30

3

263

157

20

5.0

0.0256

1.55 (1.05 – 2.29)

5.2

0.0232

1.67 (1.07 – 2.61)

0.9

0.35349

1.78 (0.52 – 6.09)