From: Rifaximin for maintenance therapy in antibiotic-dependent pouchitis
Parameter | Remission at 3 months (n = 33) | Relapse at 3 months (n = 18) | P-value |
---|---|---|---|
Symptom scores* | |||
Baseline | 4 (3, 4) | 4 (3, 4) | 0.77 |
Baseline to end of induction | 3 (2, 4)† | 3 (2, 3)† | 0.18 |
End of induction to 3-month maintenance assessment | 0 | -3 (-3, -2)† | < 0.001 |
Baseline to 3-month maintenance assessment | 3 (2, 4)‡ | 0 | < 0.001 |
Endoscopy scores* | |||
Baseline | 3 (2, 3) | 3.5 (3, 5) | 0.002 |
Baseline to end of induction | 2 (2, 3)† | 3.0 (2, 4)† | 0.098 |
End of induction to 3-month maintenance assessment | 0 | -3 (-4, -2)§ | < 0.001 |
Baseline to 3-month maintenance assessment | 2.5 (2, 3)‡ | 1 (0, 1) | < 0.001 |