Types of studies: |
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- empirical studies with a minimal sample size of five subjects |
- published from 1990 on. |
Types of participants: |
- subjects are mentally retarded or have a neurological disorder1; |
- subjects are at least two years of age. |
Types of symptoms: |
- all types of observable symptoms that are related to the results of a valid reference test for diagnosing GERD, such as PH-measurement, gastrointestinal endoscopy, radiologic method for the detection of gastroesophageal reflux. |