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Table 4 Prevalence of Pathologic Esophageal Reflux Stratified by Nocturnal Gastric Breakthrough.

From: Time esophageal pH < 4 overestimates the prevalence of pathologic esophageal reflux in subjects with gastroesophageal reflux disease treated with proton pump inhibitors

  Index Study
  NAB (n = 34) No NAB (n = 12)
Pathologic Nocturnal Esophageal Acid Integrated Acidity Time pH < 4 Integrated Acidity Time pH < 4
YES 7 18 0 3
NO 27 16 12 9
  3 rd Study
  NAB (n = 140) No NAB (n = 16)
Pathologic Nocturnal Esophageal Acid Integrated Acidity Time pH < 4 Integrated Acidity Time pH < 4
YES 49 97 1 9
NO 91 43 15 7