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Table 2 Standardized Morbidity Ratio of the site specific malignancies developed before or simultaneously the diagnosis of CD

From: Delayed diagnosis of coeliac disease increases cancer risk

Cancer

Observed

Expected

SIR(95%CI)

p

Cancer for whom CD patients showed a higher risk

Non Hodgkin's lymphoma

20

4.2

4.7 (2.9–7.3)

<0.001

Colon

7

6.2

1.1 (0.68–1.56)

<0.001

Small bowel

5

0.19

25 (8.5–51.4)

<0.001

Hodgkin's lymphoma

4

0.4

10 (2.7–25)

0.01

Stomach

3

1

3 (1.3–4.9)

0.08

Cancer for whom CD patients showed a lower risk

Breast

3

14

0.2 (0.04–0.62)

<0.001

Others

13

12

1 (0.9–8.5)

0.06

TOTAL

55

42.1

1.3 (1.0–1.7)

0.001